Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 56, Issue 11, Pages 2979-2983Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201612301
Keywords
fluorophores; imaging; near-infrared
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Funding
- Fundamental Research Funds for the Central Universities [WY1514053, WY1516017]
- National Natural Science Foundation of China [21372080, 21572061, 21236002]
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Small-molecule organic fluorophores spectrally active in the 800-950 nm region are sought-after for their broad potential in biomedical and material applications. We have developed a new family of brightly fluorescent dyes (ECX) to meet this challenge. ECX dyes are transparent to the visible region, while strongly absorbing in the NIR region at approximately 880 nm. They emit at around 915 nm with a fluorescence quantum yield up to 13.3%. ECX dyes exhibit high chemostability, high photostability, and low tendency to aggregate. Other merits of ECX dyes include low degree of solvatochromism and facile post-synthetic derivatization. ECX dyes potentially make available the 800-950 nm region for spectroscopic and microscopic applications and are also expected to find broad material applications.
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