Journal
AIDS
Volume 31, Issue 5, Pages 603-611Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/QAD.0000000000001422
Keywords
hepatocellular carcinoma; HIV; management; prognosis
Categories
Funding
- National Institute for Health Research (NIHR)
- Academy of Medical Sciences
- Imperial NIHR Biomedical Research Centre (BRC)
- Academy of Medical Sciences (AMS) [AMS-SGCL13-Pinato] Funding Source: researchfish
- National Institute for Health Research [CL-2015-21-010] Funding Source: researchfish
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Liver-related morbidity and mortality is expanding in people living with HIV. Hepatocellular carcinoma (HCC), the third most lethal malignancy on a global scale, is a dominant complication of chronic liver disease and cirrhosis in patients with coexisting hepatitis. HIV infection further complicates the clinical heterogeneity of HCC, posing concurrent challenges stemming from the underlying immunological status of the patients and the ongoing need for combined antiretroviral therapy. In this article, we review the multiple clinical implications that characterize the multidisciplinary management of HCC in the context of HIV infection. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.
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