4.3 Article

A new inflammatory marker for bone loss and low bone mineral density: platelet-to-lymphocyte ratio

Journal

BIOMARKERS IN MEDICINE
Volume 11, Issue 1, Pages 4-10

Publisher

FUTURE MEDICINE LTD
DOI: 10.2217/bmm-2016-0188

Keywords

absorptiometry; bone loss; bone mineral density; dual x-ray; low-density lipoprotein cholesterol; osteoporosis; postmenopause

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Aim: The aim of the study is to assess the possible relation of platelet-to-lymphocyte ratio (PLR), neutrophil-to-platelet ratio and low-density lipoprotein cholesterol levels with low bone mineral density (BMD) in postmenopausal women. Methodology: In total, 211 postmenopausal women were divided into two groups according to their T-score results. The control group consisted of 32 and BMD group consisted of 179 patients. Electronic records of the patients were analyzed retrospectively. Results: PLR was statistically significantly higher in the BMD group. According to receiver operating characteristic analysis, PLR was found to be a discriminative factor for low BMD. Conclusion: PLR level may predict low BMD with baseline measurement in postmenopausal women.

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