Journal
BIOSENSORS & BIOELECTRONICS
Volume 89, Issue -, Pages 249-268Publisher
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2016.01.080
Keywords
Graphene; Sensor; Hydrogen peroxide; Electrochemical detection; Enzyme; Non-enzymatic sensing
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Funding
- National Natural Science Foundation of China [21575134, 21275136]
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Due to the large specific surface area, extraordinary mechanical flexibility, chemical stability, and superior electrical and thermal conductivities, graphene (G)-based materials have recently opened up an exciting field in the science and technology of two-dimensional (2D) nanomaterials with continuously growing academic and technological impetus. In the past several years, graphene-based materials have been well designed, synthesized, and investigated for sensing applications. In this review, we discuss the synthesis and application of graphene-based 2D nanomaterials for the fabrication of hydrogen peroxide (H2O2) electrochemical sensors. In particular, graphene-based nanomaterials as immobilization matrix of heme proteins for the fabrication of enzymatic H2O2 electrochemical biosensors is first summarized. Then, the application of graphene-based electrocatalysts (metal-free, noble-metals and non-noble metals) in constructing non-enzymatic H2O2 electrochemical sensors is discussed in detail. We hope that this review is helpful to push forward the advancement of this academic issue (189 references). (C) 2016 Elsevier B.V. All rights reserved.
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