Journal
CHEMICAL COMMUNICATIONS
Volume 53, Issue 22, Pages 3253-3256Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc00670e
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Funding
- National Nature Science Foundation of China [21271072, 21571062, 21471101, 21671137]
- Program for Professor of Special Appointment (Eastern Scholar) at the Shanghai Institutions of Higher Learning
- Shenzhen Government's Plan of Science and Technology [JCY20150324140036843]
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A mitochondria-targeting nanoplatform for near-infrared-light-controlled release of nitric oxide accompanied by photothermal therapy was developed, which consists of ruthenium nitrosyl functionalized N-doped graphene quantum dots and a triphenylphosphonium moiety. The nanoplatform demonstrated both in vitro and in vivo anti-tumor efficacy upon irradiation with 808 nm light.
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