Journal
BIOMEDICAL ENGINEERING-BIOMEDIZINISCHE TECHNIK
Volume 62, Issue 4, Pages 375-381Publisher
WALTER DE GRUYTER GMBH
DOI: 10.1515/bmt-2015-0247
Keywords
antibacterial; biomaterials; corrosion; Mg alloys
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Funding
- Fundamental Research Funds for the Central Universities [XDJK2014C011]
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Two major problems with magnesium (Mg) alloy biomaterials are the poor corrosion resistance and infection associated with implantation. In this study, a novel calcium phosphate (CaP)/tetracycline (TC) composite coating for Mg implants that can both improve the corrosion resistance of Mg and release a drug in a durable way is reported. Scanning electron microscope (SEM) images showed that TC additives make the CaP coating more compact and uniform. Electrochemical tests indicated CaP/TC coatings can provide excellent corrosion protection for Mg alloy substrates. Besides, TC additives can also provide effective prevention of bone infection and inflammation due to its broad-spectrum antibacterial properties. The one-step hydrothermal process reported here greatly simplified the multi-step fabrication of smart coatings reported previously.
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