4.5 Article

Selenium-Catalyzed Oxacyclization of Alkenoic Acids and Alkenols

Journal

ASIAN JOURNAL OF ORGANIC CHEMISTRY
Volume 6, Issue 8, Pages 988-992

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ajoc.201700193

Keywords

cyclization; lactones; organocatalysis; selenium; stereoselective synthesis

Funding

  1. Dipartimento di Scienze Farmaceutiche, Universita degli Studi di Perugia Fondo per il sostegno della Ricerca di Base
  2. Fondazione Cassa di Risparmio di Perugia [2014.01000.021]
  3. Regione Umbria: project POR Umbria

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A general and efficient method for the selenium-catalyzed cyclofunctionalization reaction of alkenoic acids and alkenols is presented. Hydrogen peroxide was used as the green oxidant and all of the products were obtained in very good yields.

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