Journal
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
Volume 45, Issue 8, Pages 1769-1777Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/21691401.2017.1290643
Keywords
Modification of surface; hydrophilic ZnO nanosurface; breast cancer cell lines MCF-7; wide bandgap energy; normal human fibroblast cell MRC-5; synergistic effect; high trapping states
Ask authors/readers for more resources
Novel formulations of nanocomposites derived from ZnO nanoparticles have provided potential biomedical applications as a new strategy for treatment of breast cancer. In this research, two types of ZnO nanomaterials were synthesized by sol-gel hydrothermal process and co-precipitation containing fast quenching and also surface modification methods. The cytotoxic effects on growth of the breast cancer cell lines MCF-7 were evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. Cell viability of the breast cancer cell line MCF-7 was reduced with increasing ZnO nanofluid concentrations at 48 and 72h of treatment. The IC50 value of MCF-7 cells after 72h of treatment with the first product ZnO (a) and second one ZnO (c) were measured as 51.02 and 48.63g/ml, respectively (P<0.05).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available