Journal
CHEMISTRY OF NATURAL COMPOUNDS
Volume 53, Issue 1, Pages 72-76Publisher
SPRINGER
DOI: 10.1007/s10600-017-1914-6
Keywords
Hedychium coronarium; Zingiberaceae; aerial part; labdane-type diterpenoid; hedychiumin; cytotoxic activity
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Funding
- Ministry of Science and Technology, Taiwan [NSC 101-2320-B-127-001-MY3]
- Zuoying Branch of Kaohsiung Armed Forces General Hospital [ZBH 104-21]
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A new labdane-type diterpenoid, hedychiumin (1), has been isolated from the aerial part of Hedychium coronarium, together with five known compounds, (+)-coronarin A (2), (E)-15,16-bisnorlabda-8(17),11-dien-13-one (3), calcaratarin A (4), beta-sitostenone (5), and stigmasta-4,22-dien-3-one (6). The structure of the new compound 1 was determined through spectroscopic and MS analyses. Among the isolates, hedychiumin (1) exhibited cytotoxicity, with IC50 value of 4.74 mu g/mL, against P388D1 cell line.
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