Journal
DYES AND PIGMENTS
Volume 139, Issue -, Pages 482-486Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.dyepig.2016.12.051
Keywords
Fluorescent probes; Hydrogen sulfide; 5(6)-carboxy-rhodamine; 7-Nitro-1,2,3-benzoxadiazole
Funding
- National Natural Science Foundation of China [21302114, 21172137]
- Natural Science Foundation for youth of Shanxi [2014021015-5]
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Based on the thiolysis of 7-nitro-1,2,3-benzoxadiazole (NBD) amine, a novel fluorescent probe for hydrogen sulfide was designed and synthesized, which contains 5 (6)-carboxy-rhodamine as fluorophore and NBD as hydrogen sulfide reaction group. The probe is non-fluorescent, and could selectively detect hydrogen sulfide with a big fluorescence enhancement of 160-fold and a low detection limit of 4.80 x 10(-8) mol/L. Furthermore, coupled with its good biocompatibility, the probe has been used for fluorescent bioimaging of H2S in living cells. (C) 2016 Elsevier Ltd. All rights reserved.
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