Journal
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 27, Issue 1, Pages 51-54Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2016.11.033
Keywords
p-Terphenyls; Aspergillus sp.; Anti-phytopathogenic activity
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Funding
- National Natural Science Foundation of China [21302091]
- Fundamental Research Funds for the Central Universities [KYZ201612]
- Natural Science Foundation of Jiangsu Province [SBK2015022152]
- Scientific Research Foundation for introduced talent of Nanjing Agricultural University [020-80900211]
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Five new p-terphenyls named prenylterphenyllin D (1), prenylterphenyllin E (2), 2'-O-methylprenylterphenyllin (3), 4-O-methylprenylterphenyllin (4) and 3'-O-methylterphenyllin (5) together with seven known compounds (6-12), were isolated from cultures of Aspergillus sp. YXf3. The structures of the new compounds were elucidated by extensive MS and NMR analyses. The NMR and MS data of 5 is reported for the first time, as its structure was listed in SciFinder Scholar with no associated reference. Compounds 6 and 7 were distinguished from each other on the basis of 2D NMR experiments. Compounds 1, 2, 3 and 8 showed antibacterial activities against X. oryzae pv. oryzicola Swings and E. amylovora with the same MIC values of 20 mu g/mL while 10 exhibited activities against E. amylovora with an MIC value of 10 mu g/mL. (C) 2016 Elsevier Ltd. All rights reserved.
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