4.6 Review

Recent Advances in the Synthesis and Applications of Multimodal Gold-Iron Nanoparticles

Journal

CURRENT MEDICINAL CHEMISTRY
Volume 24, Issue 5, Pages 497-511

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/0929867323666160829111531

Keywords

Bimetallic nanoparticles; Au-Fe alloy nanoparticles; MRI; fluorinated gold nanoparticles; multimodal contrast agents

Funding

  1. Italian Health Ministry Grant [GR-2009-1579849]
  2. EU Theraglio, FP7-Health-2013-Innovation Grant [602923]

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Bimetallic particles based on gold and iron have been gathering increasing interest in biomedical applications because of the synergic combination of the plasmonic features of the inert gold component with the magnetic properties of the iron or iron oxide fraction, that makes these hybrid nanomaterials suitable for imaging, therapeutic and analytical applications. In this minireview, we emphasize gold-based nanomaterials with potential for Magnetic Resonance Imaging, focusing on Au-Fe hybrid systems as potential T-2-weighted, gold-based contrast agents.

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