Journal
CHEMICAL COMMUNICATIONS
Volume 53, Issue 11, Pages 1840-1843Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc09280b
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Funding
- National Basic Research Program of China [2012CB720602]
- National Natural Science Foundation of China [21210002, 21431007, 21403209, 21533008]
- Jilin Province Science and Technology Development Plan Project [20140101039JC]
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We have demonstrated the ability of iron carboxylate metal-organic frameworks to efficiently deliver unmethylated cytosine-phosphateguanine oligonucleotides. The nanoconjugates induced a stronger immune response than did free cytosine-phosphateguanine oligonucleotides and showed T-2-magnetic resonance imaging ability both in vitro and in vivo.
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