Journal
TRANSLATIONAL LUNG CANCER RESEARCH
Volume 6, Issue 2, Pages 119-130Publisher
AME PUBL CO
DOI: 10.21037/tlcr.2017.04.03
Keywords
Immunotherapy; palliative; reirradiation; non-small cell lung cancer (NSCLC)
Categories
Ask authors/readers for more resources
Immunotherapy has revolutionized the treatment of non-small cell lung cancer (NSCLC). However, thus far, its use has only been established in patients with advanced disease either as first-line therapy in selected patients or following chemotherapy. What is not yet known is how best to incorporate radiation with immunotherapy agents. Many patients with advanced disease can benefit from palliative radiation, but the combination of radiation with immunotherapy has the potential to increase the toxicity of both modalities. Intriguingly, the combination also has the potential to enhance the efficacy of both modalities. For this reason, combining immunotherapy and radiation may help salvage patients with recurrent localized disease who are candidates for re-irradiation. We review the current data evaluating immunotherapy with both palliative radiation as well as definitive re-irradiation in NSCLC.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available