Journal
JOURNAL OF CLINICAL AND TRANSLATIONAL HEPATOLOGY
Volume 5, Issue 2, Pages 142-151Publisher
XIA & HE PUBLISHING INC
DOI: 10.14218/JCTH.2016.00069
Keywords
Hepatic encephalopathy; Cirrhosis; Lactulose; Rifaximin
Categories
Funding
- Ocera Therapeutics
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Hepatic encephalopathy is a spectrum of reversible neuropsychiatric abnormalities, seen in patients with liver dysfunction and/or portosystemic shunting. One of the most debilitating complications of cirrhosis, encephalopathy affects 30-45% of cirrhotics. In addition to significantly affecting the lives of patients and their caregivers, it is also associated with increased morbidity and mortality as well as significant utilization of health care resources. In this paper, we provide an overview on the pathophysiology, diagnosis, management and newer therapies of hepatic encephalopathy.
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