Related references
Note: Only part of the references are listed.Apurinic/apyrimidinic endonuclease-1 is associated with angiogenesis and VEGF production via upregulation of COX-2 expression in esophageal cancer tissues
Hiroyuki Nagoya et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2014)
Latency-Associated Nuclear Antigen of Kaposi Sarcoma-Associated Herpesvirus Promotes Angiogenesis through Targeting Notch Signaling Effector Hey1
Xing Wang et al.
CANCER RESEARCH (2014)
Covalent docking of large libraries for the discovery of chemical probes
Nir London et al.
NATURE CHEMICAL BIOLOGY (2014)
Inhibition of APE1/Ref-1 redox activity rescues human retinal pigment epithelial cells from oxidative stress and reduces choroidal neovascularization
Y. Li et al.
REDOX BIOLOGY (2014)
APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions
Shweta Thakur et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2014)
Inhibition of Apurinic/Apyrimidinic Endonuclease l's Redox Activity Revisited
Jun Zhang et al.
BIOCHEMISTRY (2013)
KSHV activation of VEGF secretion and invasion for endothelial cells is mediated through viral upregulation of emmprin-induced signal transduction
Lu Dai et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Construction and Manipulation of a New Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Clone
Kevin F. Brulois et al.
JOURNAL OF VIROLOGY (2012)
Multi-Target Drugs: The Trend of Drug Research and Development
Jin-Jian Lu et al.
PLOS ONE (2012)
The RBP-Jκ Binding Sites within the RTA Promoter Regulate KSHV Latent Infection and Cell Proliferation
Jie Lu et al.
PLOS PATHOGENS (2012)
KSHV induction of angiogenic and lymphangiogenic phenotypes
Terri A. DiMario et al.
FRONTIERS IN MICROBIOLOGY (2012)
NMR Studies Reveal an Unexpected Binding Site for a Redox Inhibitor of AP Endonuclease 1
Brittney A. Manvilla et al.
BIOCHEMISTRY (2011)
Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: Maintenance of tight latency with efficient reactivation upon induction
Jinjong Myoung et al.
JOURNAL OF VIROLOGICAL METHODS (2011)
Impact of APE1/Ref-1 Redox Inhibition on Pancreatic Tumor Growth
Melissa L. Fishel et al.
MOLECULAR CANCER THERAPEUTICS (2011)
Inhibition of APE1/Ref-1 redox activity with APX3330 blocks retinal angiogenesis in vitro and in vivo
Aihua Jiang et al.
VISION RESEARCH (2011)
Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers
A. Al-Attar et al.
BRITISH JOURNAL OF CANCER (2010)
Small molecule inhibitors of DNA repair nuclease activities of APE1
David M. Wilson et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2010)
Rapid Context-Dependent Ligand Desolvation in Molecular Docking
Michael M. Mysinger et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)
Novel Small-Molecule Inhibitor of Apurinic/Apyrimidinic Endonuclease 1 Blocks Proliferation and Reduces Viability of Glioblastoma Cells
Aditi Bapat et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Selecting Diversified Compounds to Build a Tangible Library for Biological and Biochemical Assays
Qiong Gu et al.
MOLECULES (2010)
Kaposi's Sarcoma Associated Herpes Virus (KSHV) Induced COX-2: A Key Factor in Latency, Inflammation, Angiogenesis, Cell Survival and Invasion
Neelam Sharma-Walia et al.
PLOS PATHOGENS (2010)
Ceramide-dependent PP2A regulation of TNFα-induced IL-8 production in respiratory epithelial cells
Timothy T. Cornell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Transcriptional Regulatory Functions of Mammalian AP-Endonuclease (APE1/Ref-1), an Essential Multifunctional Protein
Kishor K. Bhakat et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
The Many Functions of APE1/Ref-1: Not Only a DNA Repair Enzyme
Gianluca Tell et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
The Ape-1/Ref-1 Redox Antagonist E3330 Inhibits the Growth of Tumor Endothelium and Endothelial Progenitor Cells: Therapeutic Implications in Tumor Angiogenesis
Gang-Ming Zou et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2009)
Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: Small-molecule inhibition of the redox function of Ape1
Meihua Luo et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
Kaposi's sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1α to induce vascular endothelial growth factor expression
Young C. Shin et al.
CANCER RESEARCH (2008)
Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth
Melissa L. Fishel et al.
DNA REPAIR (2008)
Reactivation of Kaposi's sarcoma-associated herpesvirus from latency requires MEK/ERK, JNK and p38 multiple mitogen-activated protein kinase pathways
Jianping Xie et al.
VIROLOGY (2008)
A potential α-helix motif in the amino terminus of LANA encoded by Kaposi's sarcoma-associated herpesvirus is critical for nuclear accumulation of HIF-1α in normoxia
Qiliang Cai et al.
JOURNAL OF VIROLOGY (2007)
Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinasesv
Li-Wu Qian et al.
JOURNAL OF VIROLOGY (2007)
The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target
Melissa L. Fishel et al.
MOLECULAR ASPECTS OF MEDICINE (2007)
Systematic identification of cellular signals reactivating Kaposi sarcoma-associated herpesvirus
Fuqu Yu et al.
PLOS PATHOGENS (2007)
The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
Frank H. Niesen et al.
NATURE PROTOCOLS (2007)
Latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells activates hypoxia-induced factors
Patrick A. Carroll et al.
JOURNAL OF VIROLOGY (2006)
Modulation of Kaposi's sarcoma-associated herpesvirus infection and replication by MEK/ERK, JNK, and p38 mitogen-activated protein kinase pathways during primary infection
Hongyi Pan et al.
JOURNAL OF VIROLOGY (2006)
Retinal angiogenesis in development and disease
RF Gariano et al.
NATURE (2005)
Kaposi's sarcoma-associated herpesvirus induction of AP-1 and interleukin 6 during primary infection mediated by multiple mitogen-activated protein kinase pathways
JP Xie et al.
JOURNAL OF VIROLOGY (2005)
Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor
S Yang et al.
MOLECULAR CANCER THERAPEUTICS (2005)
Hierarchical docking of databases of multiple ligand conformations
DM Lorber et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2005)
Use of the red fluorescent protein as a marker of Kaposi's sarcoma-associated herpesvirus lytic gene expression
J Vieira et al.
VIROLOGY (2004)
Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis
A Grundhoff et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Spatial redox regulation of a critical cysteine residue of NF-κB in vivo
T Nishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jκ (CSL), the target of the Notch signaling pathway
YY Liang et al.
GENES & DEVELOPMENT (2002)
Immune reconstitution inflammatory syndrome - Emergence of a unique syndrome during highly active antiretroviral therapy
SA Shelburne et al.
MEDICINE (2002)
Update on Kaposils sarcoma and other HHV8 associated diseases. Part 1: epidemiology, environmental predispositions, clinical manifestations, and therapy
UR Hengge et al.
LANCET INFECTIOUS DISEASES (2002)
Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor constitutively activates NF-κB and induces proinflammatory cytokine via a C-terminal signaling and chemokine production determinant
M Schwarz et al.
JOURNAL OF IMMUNOLOGY (2001)
Auto-activation of the rta gene of human herpesvirus-8 Kaposi's sarcoma-associated herpesvirus
HY Deng et al.
JOURNAL OF GENERAL VIROLOGY (2000)
Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair:: the 3′ ends justify the means
CD Mol et al.
MUTATION RESEARCH-DNA REPAIR (2000)
Kaposi's sarcoma
K Antman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)