4.6 Article

Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study

Related references

Note: Only part of the references are listed.
Article Medicine, Research & Experimental

Evaluation of noncytotoxic DNMT1-depleting therapy in patients with myelodysplastic syndromes

Yogen Saunthararajah et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Article Pharmacology & Pharmacy

Subchronic Oral Toxicity Study of Decitabine in Combination With Tetrahydrouridine in CD-1 Mice

Pramod Terse et al.

INTERNATIONAL JOURNAL OF TOXICOLOGY (2014)

Article Multidisciplinary Sciences

Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A

Jian Xu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Public, Environmental & Occupational Health

Mortality Rates and Age at Death from Sickle Cell Disease: US, 1979-2005

Sophie Lanzkron et al.

PUBLIC HEALTH REPORTS (2013)

Article Oncology

Epigenetic regulation by decitabine of melanoma differentiation in vitro and in vivo

Oscar Alcazar et al.

INTERNATIONAL JOURNAL OF CANCER (2012)

Review Hematology

Fetal hemoglobin in sickle cell anemia

Idowu Akinsheye et al.

BLOOD (2011)

Article Oncology

Noncytotoxic Differentiation Treatment of Renal Cell Cancer

Soledad Negrotto et al.

CANCER RESEARCH (2011)

Article Multidisciplinary Sciences

Histone deacetylase inhibitor induces DNA damage, which normal but not transformed cells can repair

J-H. Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Hematology

Platelet count and the risk for thrombosis and death in the elderly

J. G. van der Bom et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2009)

Article Biochemistry & Molecular Biology

Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation

Lothar Schermelleh et al.

NUCLEIC ACIDS RESEARCH (2007)

Article Multidisciplinary Sciences

Fine Tuning of Globin Gene Expression by DNA Methylation

Alon Goren et al.

PLOS ONE (2006)

Article Health Care Sciences & Services

Hydroxyurea and sickle cell anemia: effect on quality of life

Samir K. Ballas et al.

HEALTH AND QUALITY OF LIFE OUTCOMES (2006)

Article Medicine, General & Internal

N-terminal pro-brain natriuretic peptide levels and risk of death in sickle cell disease

Roberto F. Machado et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)

Review Hematology

DNA hypo-methylating agents and sickle cell disease

Y Saunthararajah et al.

BRITISH JOURNAL OF HAEMATOLOGY (2004)

Article Medicine, General & Internal

Effect of hydroxyurea on mortality. and morbidity in adult sickle cell anemia - Risks and benefits up to 9 years of treatment

MH Steinberg et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)