Journal
ADVANCED MATERIALS
Volume 29, Issue 13, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201605604
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Funding
- National R&D Program for Cancer Control, Ministry of Health and Welfare, Republic of Korea [1420390]
- KIST [2E26320]
- Korea Health Promotion Institute [1420390-1] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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An efficient system for direct delivery of integral membrane proteins is successfully developed using a new biocompatible exosome-based platform. Fusogenic exosomes harboring viral fusogen, vascular stomatitis virus (VSV)-G protein, can fuse with and modify plasma membranes in a process called membrane editing. This can facilitate the transfer of biologically active membrane proteins into the target cell membranes both in vitro and in vivo.
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