Journal
ADVANCED MATERIALS
Volume 29, Issue 13, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201605754
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Funding
- National Natural Science Foundation of China [21671198, 21425103, 81401464, 21501192]
- National Key Research and Development Program of China [2016YFA0101503]
- Natural Science Foundation of Jiangsu Province [BE2016682]
- Youth Innovation Promotion Association of Chinese Academy of Sciences (CAS)
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A novel multifunctional Ag2S quantum dot (QD)-based nanomedicine of alendronate (Ald)/doxorubicin (DOX)@Ag2S is developed for highly effective bone tumor therapy in an orthotopic model. The bone-targeting and osteolysis inhibition of Ald and the chemotherapeutic effect of DOX on the bone tumor are in situ visualized by Ag2S QDs with emission in the second near-infrared window.
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