Journal
MRS COMMUNICATIONS
Volume 7, Issue 4, Pages 913-921Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1557/mrc.2017.117
Keywords
-
Categories
Funding
- Consejo Nacional de Ciencia y Tecnologia de Mexico (CONACyT) [242269]
Ask authors/readers for more resources
Gelatin/poly(epichlorohydrin-co-ethylene oxide) [GL : PECO] composites are synthesized in a one-step process by the incorporation of elastic PECO and diclofenac. [GL : PECO] fibers are prepared by Forcespinning((R)). GL : PECO fibers are capable of diclofenac, by conjugation via a labile amide linkage. Fourier transform infrared spectroscopy (FTIR) results confirmed the chemical reactions and hydrogen bonds between gelatin, PECO, and diclofenac. Diclofenac drug release from GL : PECO fibers are measured for 15 days and prolonged drug release is observed. The cell viability is studied with NIH/3T3 and excellent results are observed. The sustained drug release and cytotoxicity results reveal that GL : PECO fibers could be promising substitutes for skin tissue engineering, wound healing, and drug delivery.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available