Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2015, Issue 34, Pages 7427-7432Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201501169
Keywords
Multicomponent reactions; Hydrogen transfer; Cross-coupling; Palladium; Nitrogen heterocycles
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Funding
- Innovation Scientists and Technicians Troop Construction Projects of Henan Province [154100510015]
- Science Foundation of Henan Education Department [14A150049, 15B150008]
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An efficient protocol for the ligand-free and heterogeneous Pd/C-catalyzed one-pot, three-component synthesis of aryl-substituted benzimidazoles from benzyl alcohols by using water as the solvent was developed. The reaction involves hydrogen-transfer and Suzuki reactions. This method is quite convenient and environmentally friendly.
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