Journal
CHEMICAL COMMUNICATIONS
Volume 53, Issue 27, Pages 3846-3849Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cc09379e
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Funding
- JSPS KAKENHI [JP24685023, JP15H00718]
- Tokuyama Science Foundation
- Grants-in-Aid for Scientific Research [17H03070, 24685023, 15H00718] Funding Source: KAKEN
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We developed a one-pot synthetic technique for alternating peptides. Central to this technique is a new, catalyst-free polymerization based on Ugi's 4CC reaction. The treatment of imines with the ambident molecules bearing both an isocyanide and a carboxylic acid afforded alternating peptides.
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