Journal
APPLIED PHYSICS LETTERS
Volume 110, Issue 15, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.4980103
Keywords
-
Categories
Funding
- Gammadosi project (Inserm: Plan Physique Cancer)
- ANR France Hadron [ANR-11-INBS-0007]
- European FP7 project ULICE [228436]
- Pole-Emploi
- Agence Nationale de la Recherche (ANR) [ANR-11-INBS-0007] Funding Source: Agence Nationale de la Recherche (ANR)
Ask authors/readers for more resources
For the purpose of detecting deviations from the prescribed treatment during particle therapy, the integrals of uncollimated prompt gamma-ray timing distributions are investigated. The intention is to provide information, with a simple and cost-effective setup, independent from monitoring devices of the beamline. Measurements have been performed with 65MeV protons at a clinical cyclotron. Prompt gamma-rays emitted from the target are identified by means of time-of-flight. The proton range inside the PMMA target has been varied via a modulator wheel. The measured variation of the prompt gamma peak integrals as a function of the modulator position is consistent with simulations. With detectors covering a solid angle of 25 msr (corresponding to a diameter of 3-4 in. at a distance of 50 cm from the beam axis) and 10(8) incident protons, deviations of a few per cent in the prompt gamma-ray count rate can be detected. For the present configuration, this change in the count rate corresponds to a 3mm change in the proton range in a PMMA target. Furthermore, simulation studies show that a combination of the signals from multiple detectors may be used to detect a misplacement of the target. A different combination of these signals results in a precise number of the detected prompt gamma rays, which is independent on the actual target position. Published by AIP Publishing.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available