4.5 Review

Advances in Radical Oxidative CH Alkylation of N-Heteroarenes

Journal

CHINESE JOURNAL OF CHEMISTRY
Volume 35, Issue 3, Pages 271-279

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.201600784

Keywords

radical; oxidative coupling; CH functionalization; alkylation; heteroarenes

Funding

  1. National Natural Science Foundation of China [21202121]

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This review summarizes recent development in CH alkylation of N-heteroarenes via the radical oxidative coupling process. A variety of alkyl radical sources (including alkanes, ethers, alcohols, carboxylic acids, organoboranes, and some other alkane derivatives) for CH alkylation of N-heteroarenes are reviewed.

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