Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 23, Issue 14, Pages 3276-3279Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201700233
Keywords
-
Categories
Funding
- Chinese Scholarship Council
Ask authors/readers for more resources
Flavones are important natural products with diverse biological activities. In this study, a novel procedure for the carbonylative synthesis of flavones has been developed by using simple phenols and internal alkynes as the substrates. Various flavones were isolated in moderate to good yields with excellent regioselectivity and functional group tolerance by using an iridium catalyst system. Notably, this is the first example of direct carbonylative annulation of non-preactivated phenols and alkynes to produce flavones, with the choice of ligand proving to be critical for the success of this transformation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available