Journal
CLINICS IN CHEST MEDICINE
Volume 38, Issue 1, Pages 29-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.ccm.2016.11.010
Keywords
Respiratory syncytial virus; Bronchiolitis; Chronic obstructive pulmonary disease; Antivirals; Asthma; Vaccines; Adults
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Respiratory syncytial virus (RSV) is the single most important cause of severe respiratory infection in very young infants. It has also been recently recognized as a significant cause of severe illness in elderly adults, those with underlying cardiopulmonary disease, and the immunocompromised. RSV is suspected of playing a major role in the development of asthma. Prophylaxis in high-risk infants using a monoclonal antibody is the only effective specific therapy available but recent breakthroughs in vaccine design and antiviral drugs offer the promise of effective prophylactic and therapeutic agents against RSV.
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