Journal
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION
Volume 16, Issue 1, Pages 175-186Publisher
SPRINGER
DOI: 10.1007/s11469-017-9854-8
Keywords
Perinatal; Screening; Psychometric properties; SRQ-20; EPDS; Low- and middle-income countries
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Funding
- Medical Research Council of South Africa
- Bill and Melinda Gates Foundation [OPP1017641]
- National Institute of Mental Health Brain Disorders in the Developing World: Research Across the Lifespan program [1R21MH098662-01]
- Bill and Melinda Gates Foundation [OPP1017641] Funding Source: Bill and Melinda Gates Foundation
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We assessed the sensitivity and specificity of the Self-Reporting Questionnaire (SRQ-20) and the Edinburgh Postnatal Depression Scale (EPDS), against the major depression module of the Mini International Neuropsychiatric Interview (MINI). Data were utilised from antenatal (n = 296) and postnatal participants (n = 366) in the Drakenstein Child Health Study (DCHS), a multidisciplinary birth cohort investigating the determinants of child health. Mothers were interviewed using the SRQ-20, the EPDS and the MINI. Receiver operating characteristic (ROC) curve analysis was performed in order to establish optimal cut-off scores. Current major depressive episode was diagnosed in 5% of antenatal and 4% of postnatal participants. At widely used threshold scores, the sensitivity of the tools ranged from 50 to 67%, although the positive predictive values at these scores were much lower (14-25%). Both tools perform acceptably in identifying mothers at risk for major depression perinatally. In identifying appropriate cut-off scores, optimising specificity and maintaining at least 30% sensitivity seems to be a feasible approach given the resourcing of South African mental health services.
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