Related references
Note: Only part of the references are listed.Pesticides: an update of human exposure and toxicity
Sara Mostafalou et al.
ARCHIVES OF TOXICOLOGY (2017)
Exposure to pesticides and the associated human health effects
Ki-Hyun Kim et al.
SCIENCE OF THE TOTAL ENVIRONMENT (2017)
Non-Animal Approaches for Toxicokinetics in Risk Evaluations of Food Chemicals
Ans Punt et al.
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION (2017)
QSAR model for blood-brain barrier permeation
Andrey A. Toropov et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2017)
Neurotoxicity in Preclinical Models of Occupational Exposure to Organophosphorus Compounds
Jaymie R. Voorhees et al.
FRONTIERS IN NEUROSCIENCE (2017)
Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin
Lisa Chedik et al.
PLOS ONE (2017)
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
Antoine Daina et al.
SCIENTIFIC REPORTS (2017)
Integration of in silico methods and computational systems biology to explore endocrine-disrupting chemical binding with nuclear hormone receptors
P. Ruiz et al.
CHEMOSPHERE (2017)
Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination
Christopher R. Jones et al.
AAPS JOURNAL (2016)
A BOILED-Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules
Antoine Daina et al.
CHEMMEDCHEM (2016)
The Utilization of the Monte Carlo Technique for Rational Drug Discovery
Mariya A. Toropova et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2016)
Potential role of organochlorine pesticides in the pathogenesis of neurodevelopmental, neurodegenerative, and neurobehavioral disorders: A review
Seyed Soheil Saeedi Saravi et al.
LIFE SCIENCES (2016)
Modeling and simulation of organophosphate-induced neurotoxicity: Prediction and validation by experimental studies
Renaud Greget et al.
NEUROTOXICOLOGY (2016)
Plasma protein binding limits the blood brain barrier permeation of the pyrethroid insecticide, deltamethrin
Manoj Amaraneni et al.
TOXICOLOGY LETTERS (2016)
Human Elimination of Organochlorine Pesticides: Blood, Urine, and Sweat Study
Stephen J. Genuis et al.
BIOMED RESEARCH INTERNATIONAL (2016)
The pharmacokinetic properties of bifenthrin in the rat following multiple routes of exposure
Derek Gammon et al.
PEST MANAGEMENT SCIENCE (2015)
P-Glycoprotein Transport of Neurotoxic Pesticides
Sarah E. Lacher et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2015)
Stereoselectivity of chiral drug transport: a focus on enantiomer-transporter interaction
Quan Zhou et al.
DRUG METABOLISM REVIEWS (2014)
In vivo methods for drug absorption - Comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects
Erik Sjogren et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2014)
Animal versus human oral drug bioavailability: Do they correlate?
Helen Musther et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2014)
Regulation of Hepatic Drug Transporter Activity and Expression by Organochlorine Pesticides
Simon Bucher et al.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2014)
In Silico ADMET Prediction: Recent Advances, Current Challenges and Future Trends
Feixiong Cheng et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)
Drug targeting to brain: a systematic approach to study the factors, parameters and approaches for prediction of permeability of drugs across BBB
Kalpana Nagpal et al.
EXPERT OPINION ON DRUG DELIVERY (2013)
Transient alterations of the blood-brain barrier tight junction and receptor potential channel gene expression by chlorpyrifos
Wen Li et al.
JOURNAL OF APPLIED TOXICOLOGY (2013)
Lack of P-Glycoprotein-Mediated Efflux and the Potential Involvement of an Influx Transport Process Contributing to the Intestinal Uptake of Deltamethrin, cis-Permethrin, and trans-Permethrin
Jason Zastre et al.
TOXICOLOGICAL SCIENCES (2013)
Pesticides and human chronic diseases: Evidences, mechanisms, and perspectives
Sara Mostafalou et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2013)
Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches
Sandra Coecke et al.
TOXICOLOGY IN VITRO (2013)
Transporters and Drug-Drug Interactions: Important Determinants of Drug Disposition and Effects
Joerg Koenig et al.
PHARMACOLOGICAL REVIEWS (2013)
Molecular mechanisms of pyrethroid insecticide neurotoxicity: recent advances
David M. Soderlund
ARCHIVES OF TOXICOLOGY (2012)
Formation of dioxins during exposure of pesticide formulations to sunlight
Eva Holt et al.
CHEMOSPHERE (2012)
Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics
Olivier Fardel et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2012)
Preclinical in vivo ADME studies in drug development: a critical review
Mario Pellegatti
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2012)
Malathion/Oxon and Lead Acetate Increase Gene Expression and Protein Levels of Transient Receptor Potential Canonical Channel Subunits TRPC1 and TRPC4 in Rat Endothelial Cells of the Blood-Brain Barrier
Pergentino Balbuena et al.
INTERNATIONAL JOURNAL OF TOXICOLOGY (2012)
Biological monitoring for exposure to deltamethrin: A human oral dosing study and background levels in the UK general population
C. Sams et al.
TOXICOLOGY LETTERS (2012)
The developmental neurotoxicity of organophosphorus insecticides: A direct role for the oxon metabolites
John Flaskos
TOXICOLOGY LETTERS (2012)
Human Hepatic Cytochrome P450-Specific Metabolism of the Organophosphorus Pesticides Methyl Parathion and Diazinon
Corie A. Ellison et al.
DRUG METABOLISM AND DISPOSITION (2012)
Low Dose Organochlorine Pesticides and Polychlorinated Biphenyls Predict Obesity, Dyslipidemia, and Insulin Resistance among People Free of Diabetes
Duk-Hee Lee et al.
PLOS ONE (2011)
Pesticide Exposure, Safety Issues, and Risk Assessment Indicators
Christos A. Damalas et al.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2011)
The ethics of human volunteer studies involving experimental exposure to pesticides: unanswered dilemmas
Leslie London et al.
ENVIRONMENTAL HEALTH (2010)
Persistent Organic Pollutant Exposure Leads to Insulin Resistance Syndrome
Jerome Ruzzin et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2010)
Prediction of passive blood-brain partitioning: Straightforward and effective classification models based on in silico derived physicochemical descriptors
Santiago Vilar et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2010)
QSAR Models for Reproductive Toxicity and Endocrine Disruption Activity
Marjana Novic et al.
MOLECULES (2010)
Biological monitoring for exposure to pirimicarb: Method development and a human oral dosing study
Craig Sams et al.
TOXICOLOGY LETTERS (2010)
Paraquat is excluded by the blood brain barrier in rhesus macaque: An in vivo pet study
Rachel M. Bartlett et al.
BRAIN RESEARCH (2009)
Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment
David L. Eaton et al.
CRITICAL REVIEWS IN TOXICOLOGY (2008)
Intestinal absorption of the acetamiprid neonicotinoid by Caco-2 cells: Transepithelial transport, cellular uptake and efflux
Jean-Luc Brunet et al.
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES (2008)
Cumulative risk assessment of pesticide residues in food
Alan R. Boobis et al.
TOXICOLOGY LETTERS (2008)
Toxicokinetics and tissue distribution of deltamethrin in adult Sprague-Dawley rats
Kyu-Bong Kim et al.
TOXICOLOGICAL SCIENCES (2008)
Computation of octanol-water partition coefficients by guiding an additive model with knowledge
Tiejun Cheng et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2007)
Transport of paraquat by human organic cation transporters and multidrug and toxic compound extrusion family
Ying Chen et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Pesticide testing on human subjects: Weighing benefits and risks
DB Resnik et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2005)
Pesticide residues in food - acute dietary exposure
D Hamilton et al.
PEST MANAGEMENT SCIENCE (2004)
The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability
LMS Chan et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2004)
Human intestinal absorption of imidacloprid with Caco-2 cells as enterocyte model
JL Brunet et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2004)
Fenitrothion: Toxicokinetics and toxicologic evaluation in human volunteers
J Meaklim et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2003)
In Silico ADME Prediction: Data, Models, Facts and Myths
Franco Lombardo et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2003)
Dietary effects on drug metabolism and transport
RZ Harris et al.
CLINICAL PHARMACOKINETICS (2003)
Persistent toxic chemicals in the US food supply
KS Schafer et al.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH (2002)
Exposure human to the organophosphate diazinon: data from a volunteer study with oral and dermal doses
SJ Garfitt et al.
TOXICOLOGY LETTERS (2002)
Oral and dermal exposure to propetamphos: a human volunteer study
SJ Garfitt et al.
TOXICOLOGY LETTERS (2002)
Modeling digestive tract absorption and desorption of lipophilic organic contaminants in humans
GA Moser et al.
ENVIRONMENTAL SCIENCE & TECHNOLOGY (2002)
Pharmacokinetics of methyl parathion: A comparison following single intravenous, oral or dermal administration
RE Kramer et al.
JOURNAL OF BIOMEDICAL SCIENCE (2002)
Molecular properties that influence the oral bioavailability of drug candidates
DF Veber et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Predicting ADME properties in silico:: methods and models
D Butina et al.
DRUG DISCOVERY TODAY (2002)
Computational approaches to the prediction of the blood-brain distribution
U Norinder et al.
ADVANCED DRUG DELIVERY REVIEWS (2002)