Journal
CLINICAL PHARMACOLOGY & THERAPEUTICS
Volume 101, Issue 4, Pages 453-457Publisher
WILEY
DOI: 10.1002/cpt.569
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Research aimed at more fully emulating human biology in vitro has rapidly progressed in recent years with advancements in 3D tissue engineering and microphysiological systems. The initial target of such systems has been directed towards drug and chemical safety assessment, with the goal of improving sensitivity and predictive capabilities. Here we discuss recent developments of in vitro organ culture systems, and their future applications in modeling human disease.
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