Journal
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 61, Issue 4, Pages -Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.02569-16
Keywords
ESBL; antibiotic resistance; mcr-1
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Funding
- National Natural Science Foundation of China [81361138021, 41541013]
- Fundamental Research Funds of Shandong University [2015JC011]
- Swedish Research Council, Public Health Agency of Sweden [D0879801]
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We report on the coexistence of mcr-1 and blaCTX-M in multidrugresistant, extended-spectrum beta-lactamase-producing Escherichia coli belonging to the sequence type 10 complex isolated from well water in rural China. Raoultella ornithinolytica with bla(KPC-2) was also detected in well water from the same area. This study shows that genes coding for resistance to last-resort antibiotics are present in wells in rural China, indicating a potential source of antibiotic resistance.
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