Journal
CHEMICAL COMMUNICATIONS
Volume 53, Issue 23, Pages 3327-3329Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc00693d
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Funding
- Medical Research Council [MC_UP_A024_1009]
- Simons Foundation [290362]
- Medical Research Council [MC_UP_A024_1009] Funding Source: researchfish
- MRC [MC_UP_A024_1009] Funding Source: UKRI
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A new alpha-cytidine derivative was synthesised from the prebiotic reaction of ribose aminooxazoline and dicyanoacetylene. The tetracyclic structure of the product was confirmed by X-ray diffraction and then an alternative 6-step synthetic pathway to the product was found which was suitable for large-scale synthesis.
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