Journal
JOURNAL OF PEDIATRIC GENETICS
Volume 6, Issue 1, Pages 3-17Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0036-1593840
Keywords
genomic imprinting; epigenetics; DNA methylation
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Imprinted genes are expressed in a parent of origin manner. Dysregulation of imprinted genes expression causes various disorders associated with abnormalities of growth, neurodevelopment, and metabolism. Molecular mechanisms leading to imprinting disorders and strategies for their diagnosis are discussed in this review article.
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