4.7 Article

Single-molecule imaging of telomerase activity via linear plasmon rulers

Journal

CHEMICAL COMMUNICATIONS
Volume 53, Issue 34, Pages 4710-4713

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc00626h

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Funding

  1. National Natural Science Foundation of China [21535003, 21327902]
  2. Priority Academic Program Development of Jiangsu Higher Education Institutions

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Plasmon rulers (PRs) exploit the potential of plasmon coupling between individual pairs of noble metal nanoparticles in biological processes, especially single-molecule detection. Herein, for the first time, we report a strategy based on Ag PRs for in situ monitoring of the extension process of telomerase primer (TSP) activated by a single telomerase.

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