Journal
ADVANCED SYNTHESIS & CATALYSIS
Volume 359, Issue 9, Pages 1588-1593Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201601065
Keywords
selenium catalysis; heterocycles; C-H oxidation; molecular oxygen
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Funding
- Hong Kong Polytechnic University [1BD07, PolyU 153014/15P, PolyU 5096/13P]
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An efficient selenium-catalyzed direct oxidation of benzylpyridines in aqueous DMSO has been successfully developed by using molecular oxygen as the oxidant. A variety of benzoylpyridines with broad functional group tolerance were obtained in modest to excellent yields and with exclusive chemoselectivity.
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