☆ 4.7 Article

BODIPY-based fluorescent probes for mitochondria-targeted cell imaging with superior brightness, low cytotoxicity and high photostability

DYES AND PIGMENTS (2017)

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Journal

DYES AND PIGMENTS
Volume 141, Issue -, Pages 530-535

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.dyepig.2017.03.009

Keywords

Fluorescent probe; Mitochondria; Imaging; Photostability

Categories

Chemistry, Applied Engineering, Chemical Materials Science, Textiles

Funding

  1. National Natural Science Foundation of China [21573168, 21303126]
  2. National Science Fund for Distinguished Young Scholars of China [21225313]
  3. Natural Science Foundation of Hubei Province [2014CFA003]
  4. Foundation of Hubei Key Laboratory of Pollutant Analysis & Reuse Technology [PA150102]
  5. Science and Technology Research Foundation of Hubei Provincial Department of Education [Q20162802]

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Two mitochondria-targeted fluorescent probes (TPP- and TEA-BODIPY) were rationally designed and easily synthesized. These probes can specifically stain mitochondria in living cells with superior brightness, low cytotoxicity and high photostability, thus are quite promising as mitochondrial tracking probes. (C) 2017 Elsevier Ltd. All rights reserved.

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