Journal
BIOMARKER RESEARCH
Volume 5, Issue -, Pages -Publisher
BMC
DOI: 10.1186/s40364-017-0097-4
Keywords
Bone biomarker; Bone formation; Bone resorption; Regulators; Bone turnover; Osteoporosis
Categories
Funding
- Taipei Medical University [105TMU-TMUH-09, TMU104-AE1-B28, MOST 105-2119-M-038-002-MY2, MOST 103-2113-M-003-003-MY3]
- Taipei Medical University Hospital
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Bone biomarkers included formation, resorption and regulator are released during the bone remodeling processes. These bone biomarkers have attracted much attention in the clinical assessment of osteoporosis treatment in the past decade. Combination with the measurement of bone mineral density, the clinical applications of bone biomarkers have provided comprehensive information for diagnosis of osteoporosis. However, the analytical approaches of the bone biomarkers are still the challenge for further clinical trials. In this mini-review, we have introduced the functions of bone biomarkers and then recently developed techniques for bone biomarker measurements have been systematically integrated to discuss the possibility for osteoporosis assessment in the early stage.
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