Journal
ADVANCED HEALTHCARE MATERIALS
Volume 7, Issue 8, Pages -Publisher
WILEY
DOI: 10.1002/adhm.201701161
Keywords
bioprinting; extrusion-based 3D printing; hydrogels; printing parameters
Funding
- National Institutes of Health [F32HL126406, R01AG045428, R01CA206880]
- National Science Foundation [1463689]
- Directorate For Engineering
- Div Of Civil, Mechanical, & Manufact Inn [1463689] Funding Source: National Science Foundation
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Additive manufacturing, or 3D printing, has become significantly more commonplace in tissue engineering over the past decade, as a variety of new printing materials have been developed. In extrusion-based printing, materials are used for applications that range from cell free printing to cell-laden bioinks that mimic natural tissues. Beyond single tissue applications, multi-material extrusion based printing has recently been developed to manufacture scaffolds that mimic tissue interfaces. Despite these advances, some material limitations prevent wider adoption of the extrusion-based 3D printers currently available. This progress report provides an overview of this commonly used printing strategy, as well as insight into how this technique can be improved. As such, it is hoped that the prospective report guides the inclusion of more rigorous material characterization prior to printing, thereby facilitating cross-platform utilization and reproducibility.
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