Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 95, Issue -, Pages 76-95Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2015.03.029
Keywords
Heterocycles; Pyridopyrimidine; Synthesis; Pharmacological activities
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Funding
- PHC Volubilis program
- LABEX IRON [ANR-11-LABX-0018-01]
- Region Centre/FEDER
- INCa, Ligue contre le cancer interegion du grand ouest
- Canceropole Grand Ouest CGO and its strand Valorisation des produits de la mer
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The interest in pyridopyrimidine cores for pharmaceutical products makes this scaffold a highly useful building block for organic chemistry. These derivatives have found applications in various areas of medicine such as anticancer, CNS, fungicidal, antiviral, anti-inflammatory, antimicrobial, and antibacterial therapies. This review mainly focuses on the progress achieved since 2004 in the chemistry and biological activity of pyridopyrimidines. (C) 2015 Elsevier Masson SAS. All rights reserved.
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