Journal
CLINICS IN LABORATORY MEDICINE
Volume 37, Issue 2, Pages 383-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cll.2017.01.009
Keywords
Rickettsiae; Taxonomy; Rickettsioses; Pathogenesis; Transmission; Epidemiology; Clinical manifestations; Laboratory diagnosis
Categories
Funding
- NIAID NIH HHS [R21 AI101413] Funding Source: Medline
Ask authors/readers for more resources
With advances in molecular genetics, more pathogenic rickettsia] species have been identified. Pathogenic rickettsiae are transmitted by vectors, such as arthropods, into the patient's skin and then spread into the micro vascular endothelial cells. Clinical manifestations are characterized by fever with headache and myalgias, followed by rash 3 to 5 days later. The undifferentiated nature of clinical symptoms, knowledge of the epidemiology, and the patient's history of travel and exposure to arthropod vectors are critical to the empiric administration of antimicrobial therapy. Doxycycline is currently the most effective antibiotic for treatment of all spotted fever group and typhus group rickettsioses.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available