Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 97, Issue -, Pages 830-870Publisher
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.ejmech.2014.11.033
Keywords
1,2,4-Triazole-3-thione; Ribavirin; Fluconazole; Anastrozole; Etodolac 1,2,4-triazole; Diflunisal 1,2,4-triazole
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Triazoles are heterocyclic compounds which have a five-membered ring of two carbon atoms and three nitrogen atoms. These structures have been interest in the development of novel compounds with anticonvulsant, antidepressant, antioxidant, anti-inflammatory, analgesic, antinociceptive, antibacterial, antimycobacterial, antifungal, antiviral, anticancer, anti-parasitic, anti-urease and other activities. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. This review contains various pharmacological activities of 1,2,4-triazole-3-thiones in one place and it is also the milestone for the new research towards this moiety. (C) 2014 Elsevier Masson SAS. All rights reserved.
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