Journal
CARBOHYDRATE POLYMERS
Volume 165, Issue -, Pages 313-321Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2017.02.064
Keywords
Zinc; Alginate; Nanocomposite; Biomineralization; Antimicrobial activity
Categories
Funding
- Ministry of Education, Science and Technological Development of the Republic of Serbia [III 45019, OI 172057]
Ask authors/readers for more resources
New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents a'good strategy for designing multifunctional biomaterials for potential biomedical applications. (C) 2017 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available