Journal
ACS NANO
Volume 11, Issue 6, Pages 5195-5214Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsnano.7b01493
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Funding
- Tec de Monterrey
- MIT Nanotechnology Program
- MIT International Science and Technology Initiatives (MISTI)
- Department of Chemical Engineering at Northeastern University
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We discuss the state of the art and innovative micro- and nano scale technologies that are finding niches and opening up new opportunities in medicine, particularly in diagnostic and therapeutic applications. We take the design of point-of-care applications and the capture of circulating tumor cells as illustrative examples of the integration of micro- and nanotechnologies into solutions of diagnostic challenges. We describe several novel nanotechnologies that enable imaging cellular structures and molecular events. In therapeutics, we describe the utilization of micro- and nanotechnologies in applications including drug delivery, tissue engineering, and pharmaceutical development/testing. In addition, we discuss relevant challenges that micro- and nanotechnologies face in achieving cost-effective and widespread clinical implementation as well as forecasted applications of micro- and nanotechnologies in medicine.
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