4.7 Article

The Third Ambient Aspirin Polymorph

Journal

CRYSTAL GROWTH & DESIGN
Volume 17, Issue 6, Pages 3562-3566

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.cgd.7b00673

Keywords

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Funding

  1. Materials Research Science and Engineering Center (MRSEC) program of the National Science Foundation (NSF) [DMR-1420073]
  2. National Nuclear Security Administration under the Stewardship Science Academic Alliances program through DOE [DE-NA0001982]
  3. NSF [DMR-1608374, DMR-1105000]
  4. DOE Office of Science [DE-AC02-06CH11357]
  5. Center for Functional Nanomaterials at Brookhaven National Laboratory [DE-AC02-98CH10086]
  6. Direct For Mathematical & Physical Scien
  7. Division Of Materials Research [1105000] Funding Source: National Science Foundation
  8. Division Of Materials Research
  9. Direct For Mathematical & Physical Scien [1608374] Funding Source: National Science Foundation

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Polymorphism of aspirin (acetylsalicylic acid), one of the most widely consumed medications, was equivocal until the structure of a second polymorph II, similar in structure to the original form I, was reported in 2005. Here, the third ambient polymorph of aspirin is described. It was crystallized from the melt, and its structure was determined using a combination of X-ray powder diffraction analysis and crystal structure prediction algorithms.

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