4.2 Article

Modified Carba NP test for the detection of carbapenemase production in gram-negative rods: optimized handling of multiple samples

Journal

BRAZILIAN JOURNAL OF MICROBIOLOGY
Volume 48, Issue 2, Pages 242-245

Publisher

SOC BRASILEIRA MICROBIOLOGIA
DOI: 10.1016/j.bjm.2016.09.015

Keywords

Carbapenemases; Diagnostics; Gram-negative bacteria

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Funding

  1. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
  2. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
  3. Fundacao Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ)

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The modified Carba NP test presented here may be a valuable tool for laboratories interested in investigating a large number of carbapenemase-producing bacteria in a less-costly way. The test was evaluated against 48 carbapenemase-producing and carbapene-masenon-producing gram-negative bacteria. No false-positive results were obtained, but false-negative results were observed with OXA-23- and GES-carbapenemase-producing isolates. Aeromonas sp. are not testable by Modified Carba NP. (C) 2016 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda.

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