Journal
BMC MUSCULOSKELETAL DISORDERS
Volume 18, Issue -, Pages -Publisher
BMC
DOI: 10.1186/s12891-017-1565-6
Keywords
Thyroid function; Thyroid stimulating hormone; Osteoarthritis; Hip joint replacement; Knee joint replacement
Categories
Funding
- Liaison Committee
- Dr. Egil Kjeldaas foundation (Lege Egil Kjeldaas legat)
- Norwegian Orthopaedic Association
- Nord-Trondelag Hospital Trust
- Levanger Hospital
Ask authors/readers for more resources
Background: To study whether thyroid function was associated with risk of hip or knee replacement due to primary osteoarthritis. Methods: In a prospective cohort study, data from the second and third survey of the Nord-Trondelag Health Study were linked to the Norwegian Arthroplasty Register in order to identify total hip or knee replacement as a result of primary osteoarthritis. Results: Among 37 891 participants without previously known thyroid disease we recorded 978 total hip replacements (THRs) and 538 total knee replacements (TKRs) during a median follow-up time of 15.7 years. The analyses were adjusted for sex, age, BMI (body mass index), smoking, physical activity and diabetes. We did not find any association between TSH (thyroid stimulating hormone) and THR or TKR due to osteoarthritis. Neither were changes in TSH over time, or overt hypo-or hyperthyroidism, associated with incidence of THR or TKR. Conclusion: No association was found between thyroid function and hip or knee joint replacement due to osteoarthritis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available