4.7 Article

A DNA-gold nanoparticle hybrid hydrogel network prepared by enzymatic reaction

Journal

CHEMICAL COMMUNICATIONS
Volume 53, Issue 43, Pages 5802-5805

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc02435e

Keywords

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Funding

  1. Special Coordination Funds for Promoting Science and Technology, Creation of Innovation Centers for Advanced Interdisciplinary Research Areas (iBioK), MEXT, Japan
  2. Takeda Science Foundation
  3. JSPS KAKENHI [16H04577, 16K14491]
  4. Grants-in-Aid for Scientific Research [16K14491] Funding Source: KAKEN

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We report a DNA-gold nanoparticle (AuNP) hybrid hydrogel in which the AuNPs crosslink enzymatically synthesized DNA to form a gel network. PCR-elongated DNA and AuNPs act as a one-dimensional polymer and cross-linkers, respectively. The DNA-AuNP hydrogel has the functional properties of both long DNA and the AuNPs.

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