Journal
BIOTECHNOLOGY FOR BIOFUELS
Volume 10, Issue -, Pages -Publisher
BMC
DOI: 10.1186/s13068-017-0841-x
Keywords
Plant biomass degradation; Transcription regulation; CAZy genes; Fungi; Bioeconomy
Funding
- SURF Foundation [e-infra130078]
- Dutch Technology Foundation STW
- Applied Science division of NWO
- Technology Program of the Ministry of Economic Affairs [016.130.609]
- Netherlands Organisation for Scientific Research (NWO)
- Netherlands Genomics Initiative [93511035]
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Fungi play a major role in the global carbon cycle because of their ability to utilize plant biomass (polysaccharides, proteins, and lignin) as carbon source. Due to the complexity and heterogenic composition of plant biomass, fungi need to produce a broad range of degrading enzymes, matching the composition of (part of) the prevalent substrate. This process is dependent on a network of regulators that not only control the extracellular enzymes that degrade the biomass, but also the metabolic pathways needed to metabolize the resulting monomers. This review will summarize the current knowledge on regulation of plant biomass utilization in fungi and compare the differences between fungal species, focusing in particular on the presence or absence of the regulators involved in this process.
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