Journal
BIOCONJUGATE CHEMISTRY
Volume 28, Issue 5, Pages 1382-1390Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.bioconjchem.7b00076
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- University of Bologna
- University of Torino
- Institute for Maternal and Child Health IRCCS Burlo Garofolo
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In this work, iron/silica/gold core-shell nanoparticles (Fe3O4@SiO2@Au NPs) characterized by magnetic and optical properties have been synthesized to obtain a promising theranostic platform. To improve their biocompatibility, the obtained multilayer nanoparticles have been entrapped in polymeric micelles, decorated with folic acid moieties, and tested in vivo for photoacoustic and magnetic resonance imaging detection of ovarian cancer.
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