Journal
RSC ADVANCES
Volume 7, Issue 40, Pages 25031-25040Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ra02574b
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Funding
- National Natural Science Foundation of China [21602022]
- Open Project Program of Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province [ARRLKF15-01]
- Chengdu University New Faculty Start-up Funding [2081915037]
- Zhejiang Provincial Natural Science Foundation [LQ14B020004]
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Palladium-catalyzed ortho-C-H olefination of phenylalanine and phenylethylamine derivatives assisted by a removable picolinamide group has been achieved. This protocol shows broad substrate scope, functional tolerance and moderate to high yields, thus affording a practical approach for the direct modification of phenylalanine and phenylethylamine derivatives.
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