4.7 Article

Polydopamine nanocoated whole-cell asymmetric biocatalysts

Journal

CHEMICAL COMMUNICATIONS
Volume 53, Issue 49, Pages 6617-6620

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc01283g

Keywords

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Funding

  1. PCSIRT [IRT_15R52]
  2. NSFC [U1663225, U1662134, 51472190, 51611530672, 51503166]
  3. ISTCP [2015DFE52870]
  4. HPNSF [2016CFA033]
  5. CNPC [PPC2016007]
  6. China Scholarship Council (CSC)

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Our whole-cell biocatalyst with a polydopamine nanocoating shows high catalytic activity (5 times better productivity than the native cell) and reusability (84% of the initial yield after 5 batches, 8 times higher than the native cell) in asymmetric reduction. It also integrates with titania, silica, and magnetic nanoparticles for multi-functionalization.

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